Quadros Bio

For Product Teams

I need help with field trial design.

Support for biologicals validation pipeline design, tailored field trial architecture across agroecological zones, and the pre-fundraising evidence work that turns promising biology into a credible product.

Built on plant-microbe-environment systems thinking, not standardised templates.

Who This Is For

Teams working through validation, not pitch refinement.

  • Biologicals product teams entering field validation
  • Companies running multi-site trials across agroecological zones
  • Teams preparing trial data for regulatory submission (CFIA, EPA, MAPA)
  • Founders preparing scientific evidence for the next fundraise
  • R&D groups whose lab and greenhouse results aren't translating to the field

Where Trials Go Wrong

Six failure modes that show up in nearly every biologicals trial we review.

Lab signals that don't translate

A strain that lit up a Petri dish or a greenhouse pot fails to produce a measurable effect under real field conditions. Often because the trial wasn't designed to reveal the conditions under which it actually works.

Single-site, single-season blind spots

A trial run at one site for one season tells you almost nothing about commercial behavior. Variability across agroecological zones and years is where biologicals live and die.

Missing or weak controls

Without rigorous untreated and reference-product controls, treatment effects disappear into noise. Investors and regulators see the gap immediately.

Mismatched endpoints

Measuring chlorophyll when the value claim is yield, or measuring yield when the regulatory claim is biocontrol. The endpoint has to match the claim, the regulator, and the buyer.

Plant-microbe-environment interactions ignored

Biological performance depends on three interacting systems. Trial designs that treat the product as a chemical input miss the interactions that drive real-world performance.

Statistical significance is not commercial significance

A p-value under 0.05 across a 2-acre plot does not equal a product that grows margin in farmers' fields. Trials need to predict commercial behavior, not just clear a statistical bar.

How We Help

Trial design built for the system where your product actually has to work.

Biological product performance depends on three interacting systems: the plant, its microbial community, and the soil-climate environment around them. Quadros Bio designs and reviews field trial programmes that account for all three across agroecological zones, microbial compatibility, application timing, and environmental variability.

The result is trial data that holds up under regulatory review and predicts commercial performance in the field, not just statistical significance in a single plot.

Engagements

Three ways to engage.

01

Field Trial Design Review

Independent audit of a planned or in-flight field trial. Identifies gaps in design, controls, endpoints, agroecological coverage, statistical power, and regulatory alignment before they become expensive.

Best for

Teams about to launch a trial or finalising a protocol with a CRO or field partner.

Deliverable

Written assessment with prioritised recommendations and a redesign brief.

02

Validation Pipeline Design

Architecture for a multi-site, multi-season validation programme from lab through greenhouse through field, sequenced to support regulatory filing and commercial launch.

Best for

Companies moving from R&D into the validation phase of product development.

Deliverable

Full pipeline blueprint, site and partner recommendations, agroecological zone coverage map, milestone and decision-gate schedule.

03

Pre-Fundraising Evidence Package

Take the trial data you already have and structure it into an investor-grade evidence package. Identify what is strong, what is missing, and what needs to happen before the next raise.

Best for

Teams six to twelve months from fundraising who want to know what their data actually shows.

Deliverable

Evidence assessment, technical-narrative draft, gap map with a prioritised closure plan.

Pricing is tailored to the scope and complexity of each engagement and discussed during an initial consultation.

The Process

Three steps from inquiry to trial-ready.

01

Discovery Call

We map your product, the claim you need to support, the regulatory geography, and the trial decisions you have already made or are about to make.

02

Design or Review

Depending on the engagement, we either design the trial programme or audit what you have planned. Output is a concrete document, not a generic checklist.

03

Implementation Support

Optional ongoing involvement during execution: oversight of CRO or field partners, statistical analysis, protocol adjustments, and a final report you can hand to investors or regulators.

Why us

Field trial design built on the work, not the literature.

George Weston Foundation Programme

Led a four-phase, $245K industry-funded research programme on plant-microbe interactions in controlled-environment agriculture. 12+ strains screened, GC-MS flavour profiling, four formulation formats, patent milestone reached.

Earth Microbial En-Turf

Designed, tested, and validated a microbial inoculant specifically for golf-course turfgrass. Formulation refined through multiple iteration cycles and positioned for commercial launch.

Tropical No-Till Maize Systems

PhD work on biological nitrogen fixation by Azospirillum spp. in Brazilian tropical no-tillage maize, including the influence of legume cover crops on soil microbial diversity and fertility.

Brazilian + North American Field Networks

Active research relationships with Embrapa and Brazilian federal universities, plus regulatory familiarity across CFIA, EPA, USDA, and MAPA. Trial designs that anticipate regulatory expectations on both sides of the equator.

Confidential by default. Not sold. Not published. Not shared without permission.

Tell us about your trial

Trial-ready evidence starts with trial-ready design.

Schedule a 20-minute discovery call. We will map your product, your claim, your geography, and what your current trial plan is or is not designed to prove.