For Product Teams
Field trial design for biological products across agroecological zones.
Support for biologicals validation pipeline design, tailored field trial architecture across agroecological zones, and the evidence package required before a fundraise.
Built on plant-microbe-environment systems thinking.
Who This Is For
Teams working through validation.
- →Biologicals product teams entering field validation
- →Companies running multi-site trials across agroecological zones
- →Teams preparing trial data for regulatory submission (CFIA, EPA, MAPA)
- →Founders preparing scientific evidence for the next fundraise
- →R&D groups whose lab and greenhouse results aren't translating to the field
Where trials go wrong
Six failure modes recurrent in biologicals trials.
Lab signals that don't translate
A strain with a clear effect in a Petri dish or greenhouse pot produces no measurable effect under field conditions, often because the trial was not designed to reveal the conditions under which the effect appears.
Single-site, single-season blind spots
A trial run at one site for one season provides limited evidence about transferability across environments and years. Variability across agroecological zones and years determines commercial performance.
Missing or weak controls
Without untreated and reference-product controls, treatment effects are not separable from noise.
Mismatched endpoints
Measuring chlorophyll when the value claim is yield, or measuring yield when the regulatory claim is biocontrol. The endpoint has to match the claim, the regulator, and the buyer.
Plant-microbe-environment interactions ignored
Biological performance depends on three interacting systems. Trial designs that treat the product as a chemical input miss the interactions that drive real-world performance.
Statistical significance is not commercial significance
Statistical significance does not establish agronomic or commercial significance; effect size, consistency, environmental dependence, and practical value must also be considered.
How We Help
Trial design built for the system the product has to work in.
Biological product performance depends on three interacting systems: the plant, its microbial community, and the soil-climate environment around them. Quadros Bio designs and reviews field trial programmes that account for all three across agroecological zones, microbial compatibility, application timing, and environmental variability.
Trials are designed to test the claim under the conditions the product must perform in, across sites and seasons, with controls and endpoints matched to the regulatory and commercial claim.
Engagements
Three ways to engage.
01
Field Trial Design Review
Independent audit of a planned or in-flight field trial. Identifies gaps in design, controls, endpoints, agroecological coverage, statistical power, and regulatory alignment.
Best for
Teams about to launch a trial or finalising a protocol with a CRO or field partner.
Deliverable
Written assessment with prioritised recommendations and a redesign brief.
02
Validation Pipeline Design
Architecture for a multi-site, multi-season validation programme from lab through greenhouse through field, sequenced to support regulatory filing and commercial launch.
Best for
Companies moving from R&D into the validation phase of product development.
Deliverable
Full pipeline blueprint, site and partner recommendations, agroecological zone coverage map, milestone and decision-gate schedule.
03
Pre-Fundraising Evidence Package
Existing trial data is assessed and structured into an evidence package: what the data supports, what is absent, and what must be closed before a raise. Identify what is strong, what is missing, and what needs to happen before the next raise.
Best for
Teams six to twelve months from fundraising who want to know what their data actually shows.
Deliverable
Evidence assessment, technical-narrative draft, gap map with a prioritised closure plan.
Pricing is tailored to the scope and complexity of each engagement and discussed during an initial consultation.
The Process
Three steps from inquiry to trial-ready.
01
Discovery Call
The discovery call establishes the product, the claim to be supported, the regulatory geography, and the trial decisions already made.
02
Design or Review
Depending on the engagement, we either design the trial programme or audit what you have planned. Output is a written design document.
03
Implementation Support
Optional ongoing involvement during execution: oversight of CRO or field partners, statistical analysis, protocol adjustments, and a final report you can hand to investors or regulators.
Why us
Field trial design built on primary research and product development.
2,000+ Isolates. ~200 Strains Field-Tested.
Career-spanning isolation work across 14 crop systems in 5 countries, from rhizosphere to endophyte to seed-borne. Approximately 200 strains advanced past in vitro screening into greenhouse and field trials. Genomic sequencing was used in strain selection.
Published Primary Research
Primary research in ISME Journal, Applied and Environmental Microbiology, Frontiers, and PLoS ONE. Topics span nitrogen fixation, microbial inoculant formulation, plant-microbe metabolomics, biocontrol, and soil microbiome recovery.
Isolation to Shelf: The Full Product Pipeline.
Dr. Quadros has built liquid, gel, powder and seed-coating formulations for bacterial inoculants, including shelf-life and viability testing. From strain isolation through formulation design, shelf-stability testing, and field validation across corn, wheat, soybean, canola, strawberry, leafy greens, and turfgrass.
Brazil + North America: Regulatory on Both Sides.
Active research networks with Embrapa and Brazilian federal universities, plus direct regulatory experience across CFIA, EPA, USDA, and MAPA/SISGEN, with multiple product registrations submitted in North America. Trial designs that anticipate registration requirements on both sides of the equator.
Confidential by default. Not sold. Not published. Not shared without permission.
Tell us about your trial
Trial design reviewed before the trial runs.
Send us your trial details. We respond within two business days. The discovery call maps your product, your claim, your geography, and what your current trial plan is or is not designed to prove.